Men and women who smoked marijuana before age 17 are 3.5 times as likely to attempt suicide as those who started later.

Heroin was first synthesized in 1874 by C. R. Alder Wright, an English chemist working at St. Mary's Hospital Medical School in London, England.

Crime and heroin addiction have long been associated together. This is due to many reasons such as the fact that heroin importation and distribution are illegal. Also, heroin and crime are synonymous because many addicted people turn to theft and prostitution to obtain money to buy the drug. Violent competition between drug dealers has resulted in many murders and the deaths of innocent bystanders. From 1979 through 1990 arrests for heroin manufacture, sale, or possession in the United States held steady, but in the 1990s arrests rose as the drug's popularity began to increase once more.

According to the U.S. Sentencing Commission, only 5.5% of all federal crack defendants are high-level dealers.