Withdrawal from methamphetamine can produce effects such as craving, exhaustion, depression, mental confusion, restlessness and insomnia, deep or disturbed sleep sometimes lasting up to 48 hours, extreme hunger, psychotic reaction, and anxiety reactions. The manufacture of a pound of meth creates 5-6 pounds of toxic waste. Minnesota drug officials closed down a meth lab in 2003 being operated in a ice-fishing shack. The cookers were dumping waste into the ice hole, poisoning the lake. Most babies of heroin users suffer from withdrawal symptoms after birth, including fever, sneezing, trembling, irritability, diarrhea, vomiting, continual crying and, occasionally, seizures. Babies exposed to heroin before birth also face an increased risk of sudden infant death syndrome (SIDS). As with other amphetamines, tolerance to methamphetamine is not completely understood, but known to be sufficiently complex that it cannot be explained by any single mechanism. The extent of tolerance and the rate at which it develops varies widely between individuals, and even within one person it is highly dependent on dosage, duration of use and frequency of administration. Many cases of narcolepsy were treated with methamphetamine for years without escalating doses or any apparent loss of effect. |